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type 1 diabetes (t1d)  (Illumina Inc)


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    Illumina Inc type 1 diabetes (t1d)
    Summary of external GWAS summary statistics used
    Type 1 Diabetes (T1d), supplied by Illumina Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/type+1+diabetes+(t1d)/baits+covering+the+ebv+type+1+and+2+reference+genomes/pmc09465343-3-0-4
    Average 90 stars, based on 1 article reviews
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    1) Product Images from "Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores"

    Article Title: Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

    Journal: Human Genetics and Genomics Advances

    doi: 10.1016/j.xhgg.2022.100136

    Summary of external GWAS summary statistics used
    Figure Legend Snippet: Summary of external GWAS summary statistics used

    Techniques Used:

    Related Articles

    other:

    Article Title: Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores
    Article Snippet: Type 1 diabetes (T1D) (Illumina) , Censin et al. , 7982 , 8,996,866 , 949,334 , 0.942.



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    Summary of external GWAS summary statistics used
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    Image Search Results


    ( A ) The concentration of fasting serum Galectin-3 in healthy controls (HC, n = 132), Ab − FDR ( n = 76), Ab + FDR ( n = 30), and patients with T1D ( n = 234). Data are expressed as median ± range. ( B ) The mRNA expression levels of Galectin-3 in CD14 + monocytes isolated from patients with T1D and HC ( n = 10), calculated using the 2 −△△Ct method. ( C ) The concentration of fasting serum LPS in HC and T1D groups ( n = 56). Data are expressed as median ± range. ( D ) Correlation between serum levels of Galectin-3 and LPS in HC and patients with T1D. ( E to J ) The THP-1 cell line, THP-1–cell induced macrophages, and the RAW 264.7 cell line were treated with LPS (100 ng/ml) or vehicle for 24 hours. The mRNA expression levels of Galectin-3 [(E), (G), and (I)] and the protein concentration of Galectin-3 in the supernatant [(F), (H), and (J)] were measured. Data in (E) to (J) are representative of at least three independent experiments with similar results. Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.

    Journal: Science Advances

    Article Title: Galectin-3 exacerbates autoimmune diabetes by limiting regulatory T cell differentiation and function

    doi: 10.1126/sciadv.adz7916

    Figure Lengend Snippet: ( A ) The concentration of fasting serum Galectin-3 in healthy controls (HC, n = 132), Ab − FDR ( n = 76), Ab + FDR ( n = 30), and patients with T1D ( n = 234). Data are expressed as median ± range. ( B ) The mRNA expression levels of Galectin-3 in CD14 + monocytes isolated from patients with T1D and HC ( n = 10), calculated using the 2 −△△Ct method. ( C ) The concentration of fasting serum LPS in HC and T1D groups ( n = 56). Data are expressed as median ± range. ( D ) Correlation between serum levels of Galectin-3 and LPS in HC and patients with T1D. ( E to J ) The THP-1 cell line, THP-1–cell induced macrophages, and the RAW 264.7 cell line were treated with LPS (100 ng/ml) or vehicle for 24 hours. The mRNA expression levels of Galectin-3 [(E), (G), and (I)] and the protein concentration of Galectin-3 in the supernatant [(F), (H), and (J)] were measured. Data in (E) to (J) are representative of at least three independent experiments with similar results. Data are expressed as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.

    Article Snippet: However, the significance of circulating Galectin-3 in type 1 diabetes (T1D) remains unclear.

    Techniques: Concentration Assay, Expressing, Isolation, Protein Concentration

    Summary of external GWAS summary statistics used

    Journal: Human Genetics and Genomics Advances

    Article Title: Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

    doi: 10.1016/j.xhgg.2022.100136

    Figure Lengend Snippet: Summary of external GWAS summary statistics used

    Article Snippet: Type 1 diabetes (T1D) (Affymetrix) , Censin et al. , 5516 , 8,996,866 , 934,712 , 0.885.

    Techniques:

    Summary of external GWAS summary statistics used

    Journal: Human Genetics and Genomics Advances

    Article Title: Identifying and correcting for misspecifications in GWAS summary statistics and polygenic scores

    doi: 10.1016/j.xhgg.2022.100136

    Figure Lengend Snippet: Summary of external GWAS summary statistics used

    Article Snippet: Type 1 diabetes (T1D) (Illumina) , Censin et al. , 7982 , 8,996,866 , 949,334 , 0.942.

    Techniques: